Biological Response of Fibroblasts to Laser-Modified Titanium Surfaces was presented as part of the PERI-EDU research programme during the 9th Congress of the Polish Dental Association at Ptak Warsaw Expo.
Research question
Study design
The review searched PubMed, Scopus, Embase and Web of Science for in-vitro studies evaluating fibroblast responses to laser-modified titanium. From 427 identified records, 27 studies were included after screening; the poster reports a low risk of bias across the included evidence.
Main findings
- Laser-treated titanium generally improved fibroblast adhesion, spreading, elongated morphology and metabolic activity.
- Micro- and nanotopographies promoted cell adhesion, proliferation and alignment, while improved wettability further supported attachment.
- Biological outcomes depended strongly on wavelength, energy and irradiation protocol; optimized exposure performed better than insufficient treatment.
- Three-directional irradiation and erbium-laser protocols were among the approaches associated with favourable responses while preserving surface integrity.
Interpretation
Laser modification appears capable of supporting fibroblast behaviour and potentially improving peri-implant soft-tissue integration. The effect is protocol-dependent, so translation requires reproducible laser parameters and confirmation in clinical studies.
Download the full conference poster
The complete poster is available as a PDF, including figures, numerical results and the selected reference list.
Download poster PDF
View congress report
View abstract supplement
Funding: This work was co-funded by the European Union under grant agreement No. 2024-1-PL01-KA220-HED-000251208.
Disclaimer: Co-funded by the European Union. Views and opinions expressed are, however, those of the author(s) only and do not necessarily reflect those of the European Union or the Foundation for the Development of the Education System (FRSE). Neither the European Union nor FRSE can be held responsible for them.