From CRP to SII. Why may single inflammatory markers not be enough?
CRP, leukocytes, and pro-inflammatory cytokines are among the most recognizable markers of inflammation. In the context of peri-implantitis, they may provide valuable information about the activity of the inflammatory response, but they also have important limitations. A single marker reflects only one fragment of a complex biological process and usually does not capture the full […]
SIMREX: a project-based immune-inflammatory index in peri-implantitis
Peri-implantitis is a disease that cannot be fully described by a single parameter. Biofilm, host immune response, the patient’s systemic condition, local peri-implant factors, and potential material-related aspects all contribute to a complex clinical picture. This is why the PERI-EDU project introduces the concept of SIMREX — an immune-inflammatory response index designed specifically for peri-implant […]